عنوان مقاله [English]
نویسندگان [English]چکیده [English]
Ginger is one of the most valuable medical plants. It is a plant that contains most anti oxidant such as B, C and E vitamin. Also, this plant is effective in sexual ability. In this research, the effect of ginger extract has been investigated on hormonal axis of pituitary-gonad and spermatogenesis in mature mice of Balb/C. The used animals were 28 male mice with approximate weight about 26 to 31 grams and with the age about 60 days. The samples randomly were divided in to 4 groups that are contained control and sham and two group treatment. Treatment animals, received 50 and 100 mg/kg of mentioned extracts respectively two weeks, intraperitoneally. During mentioned period, sham group received distilled water in intrapritoneally. Control group used of food and water during. The concentration of LH, FSH and testosterone hormones was measured. Also, the number of spermatogonia, spermatocyte, sperm, spermatid, Sertoli, and Leydig cells were calculated. The concentration of LH hormone serum levels showed significant decrease in treatment 2 and the concentration of FSH hormone also in each two treatment groups in comparison with control and sham groups. The concentration of LH hormone indicated significant increase (pandlt;=0/05) in treatment 1 and the concentration of testosterone hormone in treatment 1, 2 group in comparison with control and sham groups. Also results indicated that in spermatid, sperm and leydig cell have significant increase in treatment 1, 2 in comparison with control and sham groups. So, according to obtained results and according to increasing of the number of leydig cells and testosterone concentration it can conclude that ginger may cause sex cell proliferation in adult male mice.