عنوان مقاله [English]
Leptin, after passing from sertoli-cells and entering into the balls, can cause the prevention of releasing testosterone and can control releasing glycoproteins though a paracrine network and also defect or resistance of Leptin causes extreme deficiency in the function of genitourinary system in human and animal models. As Leptin do its own physiological functions with the reaction to Leptin receptor and also leap in coding gene of Leptin receptor causes reduction in density of testosterone serum, normal sexual minority and sterility. On the other hand, any researches haven’t been conducted clearly on relationship of testosterone and Leptin in fertile and sterile men, this research has been performed, about this subject. Elisa is one of the best laboratorial and research methods all over the world and used in identifying the small amounts of vital hormones and molecules in clinical medicine and research tests. In this research, the effect of Leptin on testosterone in serum of fertile and sterile men has been researched and compared.The result is that the amount of the testosterone in sterile persons is more than fertile persons but the amount of Leptin in fertile persons is more than sterile persons. Therefore, determining the treatment strategy to cure the sterile men is the usage of effective medicines and diet with Leptin.