تاثیر فصل و سن بر روی پارامترهای اسپرمی در افراد نابارور

نوع مقاله: مقاله پژوهشی

نویسندگان

1 پژوهشگاه رویان، پژوهشکده زیست فناوری جهاد دانشگاهی، مرکز تحقیقات پزشکی تولیدمثل، گروه زیست فناوری تولیدمثل، اصفهان، ایران

2 پژوهشگاه رویان، پژوهشکده زیست فناوری جهاد دانشگاهی، مرکز تحقیقات پزشکی تولیدمثل، گروه زیست فناوری تولیدمثل، اصفهان، ایران مرکز باروری و ناباروری اصفهان، اصفهان، ایران

چکیده

تقریبا 15 درصد از زوجین نابارور هستند که ناباروری با فاکتور مردانه، در نیمی از زوجین نابارور گزارش شده است. عوامل متعددی از جمله سن و فصل بر کیفیت پارامترهای اسپرمی موثر است؛ که در موقعیت­های جغرافیایی متفاوت می­تواند نتایج متفاوتی داشته باشد. لذا در این مطالعه، تاثیر این دو فاکتور بر روی پارامترهای اسپرمی در افراد نابارور مورد بررسی قرار گرفته است. 659 نمونه مایع منی از افراد نابارور مراجعه کننده به مرکز باروری و ناباروری اصفهان، جمع­آوری گردید. ارزیابی مایع منی شامل حجم، غلظت، تحرک و مورفولوژی بر اساس معیارهای 2010 سازمان بهداشت جهانی انجام شد. آنالیز آماری به وسیله نرم­­افزار 23SPSS  انجام شد و 05/0values < p- از لحاظ آماری، معنی­دار در نظر گرفته شد. کیفیت پارامترهای اسپرمی به خصوص تعداد و تحرک اسپرم، تحت تاثیر تغییرات سن و فصل باشند. در این مطالعه، ارتباط معنی دار معکوسی بین سن مردان با تعداد و تحرک اسپرم مشاهده شد (05/0p˂). با افزایش سن، میانگین تعداد و تحرک اسپرم در افراد نابارور کاهش می­یابد و کاهش این دو پارامتر بیشتر در نیمه­ی اول سال دارای نوسانات بارزی نسبت به نیمه­ی دوم سال است. این در حالی است که متغییرهای سن و فصل بر روی مورفولوژی اسپرم تاثیری ندارد.

کلیدواژه‌ها


عنوان مقاله [English]

The Effect of Season and Age on Sperm Parameters in Infertile Men

نویسندگان [English]

  • Sh. Bakhshesh 1
  • M. Tavalaee 1
  • M.H. Nasr-Esfahani 2
1 Department of Reproductive Biotechnology, Reproductive Biomedicine Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, Iran
2 Department of Reproductive Biotechnology, Reproductive Biomedicine Research Center, Royan Institute for Biotechnology, ACECR, Isfahan, Iran; Isfahan Fertility and Infertility Center, Isfahan, Iran
چکیده [English]

Approximately 15% of couples are infertile. Male factor infertility is reported in half of infertile couples. Several factors including age, and season are effective on the quality of sperm parameters, which can have different results in different geographic locations. In this study, the effect of these two factors on sperm parameters in infertile men was investigated. Overall, 659 semen samples from infertile men referred to the Isfahan Fertility and Infertility Center, Isfahan, central Iran were collected. Semen analysis included assessment of volume, concentration, motility and morphology carried out according to WHO (2010). Statistical analyses were performed using SPSS software. Quality of sperm parameters, especially sperm motility and count were affected by the age and seasonal changes. Negative significant correlations between male age with sperm count and motility were observed (P<0.05). As the age increases, the mean of sperm count and motility in infertile men are reduced, and the reduction in these two parameters are more pronounced in the first half of the year than in the second half of the year. However, age and seasonal variations do not affect sperm morphology.
 

کلیدواژه‌ها [English]

  • Season
  • age
  • Sperm parameters
  • Male infertility
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