نوع مقاله : مقاله پژوهشی
نویسندگان
1 گروه زیست شناسی، دانشکده علوم، دانشگاه پیام نور، مرکز تهران، تهران، ایران
2 گروه زیست شناسی، دانشگاه پیام نور، مرکز اصفهان، اصفهان، ایران
چکیده
کلیدواژهها
عنوان مقاله [English]
نویسندگان [English]
The human chorionic gonadotropin (HCG) hormone is used for infertility treatment. The existence of some inflammatory factors reduces the therapeutic effect of HCG. Therefore, a complementary factor is needed to improve HCG performance. Zingiber is the oldest herbal medicines with antiinfammatory property. Thus the aim of this study was to investigate the effect of HCG and Zingiber extract on the gonads and accessory glands in the immature male rats. A total of 24 immature male Wistar rats were divided into four groups and treated with physiology serum (control), HCG hormone (experimental 1), zingiber extract (experimental 2), and HCG combined with Zingiber extract (experimental 3). After treatment, rats were autopsied. The testis and seminal vesicle were weighed. After tissue slide preparation, types A and B spermatogonia cells and primary spermatocytes were counted and the diameter of the seminiferous tubules and the thickness of the germinal layer were measured. The obtained results were analyzed using one-way analysis of variance (ANOVA) in SPSS software. The research results showed that the testicle weight in the experimental group 1 (HCG) and experimental group 3 (HCG and extract) has increased in comparison with the control group, but there is no significant difference. The weight of the seminal vesicle, number of types A and B spermatogonia cells, number of primary spermatocytes, diameter of seminiferous tubules, and thickness of the germinal layer have significantly increased in the experimental group 1 and experimental group 3 compared to control. HCG combined with Zingiber extract can positively affect the growth of gonads and accessory glands and development of spermatogenesis.
کلیدواژهها [English]